@article {62479,
	title = {Chemical constituents, in vitro anti-inflammatory, antioxidant and hemostatic activities of then-butanol extract ofHyacinthoides lingulata (Poir.) Rothm},
	journal = {Natural Product Research},
	year = {2022},
	month = {2022},
	abstract = {
	The phytochemical profile obtained from LC-ESI-MS/MS analysis of then-butanol extract (BEHL) from the North African endemic plantHyacinthoides lingulata\&nbsp;(Poir.) Rothm. brought about the identification of ten glycosylated derivatives of apigenin and luteolin flavones. For the same plant extract,in\&nbsp;vitro\&nbsp;anti-inflammatory (hypotonic induced hemolysis and heat induced haemolysis assay) and antioxidant (DPPH andβ-Carotene) activities were evaluated observing high inflammatory inhibition by protecting membrane stability of erythrocyte in both heat (84.70 {\textpm} 0.24\%) and hypotonic induced hemolysis (79.45 {\textpm} 0.12\%). A remarkable hemostatic effect was also established by measuring the coagulation time (15.95\&nbsp;{\textpm}\&nbsp;1.05 s at a dose of 1 mg/mL) of decalcified plasma related to its phytochemical content. It is the first report on combined chemical components and biological evaluation of this specific plant.

},
	isbn = {1478-6419},
	url = {https://doi.org/10.1080/14786419.2021.1937153},
	author = {HANFER, Mourad and Benramdane, Zeyneb and Cheriet, Thamere and Sarri, Djamel and Menad, Ahmed and Mancini, Ines and Seghiri, Ramdane and Ameddah, Souad}
}
