@article {62619,
	title = {Chemical constituents, in vitro anti-inflammatory, antioxidant and hemostatic activities of the n-butanol extract of Hyacinthoides lingulata (Poir.) Rothm},
	journal = {Natural Product Research},
	volume = {36},
	number = {12},
	year = {2021},
	month = {2021},
	pages = {3124-3128},
	abstract = {
	The phytochemical profile obtained from LC-ESI-MS/MS analysis of the\&nbsp;n-butanol extract (BEHL) from the North African endemic plant\&nbsp;Hyacinthoides lingulata\&nbsp;(Poir.) Rothm. brought about the identification of ten glycosylated derivatives of apigenin and luteolin flavones. For the same plant extract,\&nbsp;in vitro\&nbsp;anti-inflammatory (hypotonic induced hemolysis and heat induced haemolysis assay) and antioxidant (DPPH and\&nbsp;β-Carotene) activities were evaluated observing high inflammatory inhibition by protecting membrane stability of erythrocyte in both heat (84.70 {\textpm} 0.24\%) and hypotonic induced hemolysis (79.45 {\textpm} 0.12\%). A remarkable hemostatic effect was also established by measuring the coagulation time (15.95 {\textpm} 1.05 s at a dose of 1 mg/mL) of decalcified plasma related to its phytochemical content. It is the first report on combined chemical components and biological evaluation of this specific plant.

},
	isbn = {1478-6419},
	url = {https://pubmed.ncbi.nlm.nih.gov/34121529/},
	author = {HANFER, Mourad and Benramdane, Zeyneb and Cheriet, Thamere and Sarri, Djamel and Menad, Ahmed and Mancini, Ines and Seghiri, Ramdane and Ameddah, Souad}
}
