@article {66188,
	title = {New steroidal glycosides from Dracaena marginata, Dracaena fragrans and Allium flavum},
	journal = {Planta MedicaPlanta Medica},
	volume = {80},
	year = {2014},
	month = {2014},
	abstract = {Steroidal saponins are a class of glycosides occurring in many plant species. The aglycon part of these glycosides is constituted by a furostane or spirostane-type skeleton, rarely cholestane. These saponins are known for their interesting pharmacological activities such as antifungal, anti-ischemia, antispasmodic, cytotoxic, haemolytic [1 {\textendash} 3], and anti-inflammatory properties [4]. The aim of our researches was the isolation and structural elucidation of the steroidal saponins from the biodiversity. In this context, the study of three plants species,\&nbsp;Dracaena marginata,\&nbsp;D. fragrans\&nbsp;(Asparagaceae) and\&nbsp;Allium flavum\&nbsp;(Amaryllidaceae) led to isolation of twenty-one natural glycosides by column chromatography on Sephadex LH-20, medium pressure liquid chromatography and vacuum liquid chromatography on silica gel and reversed-phase RP-18 silica gel. The structures were elucidated by a detailed spectral analysis by 600 MHz 2D-NMR (COSY, TOCSY, ROESY/NOESY, HSQC, HMBC/HMQC), and mass spectrometry. Six new compounds were characterized as spirostane and furostane- type glycosides from\&nbsp;D. marginata\&nbsp;(1 {\textendash} 3) and from\&nbsp;A. flavum\&nbsp;(4 {\textendash} 6). The presence of a 4-O-sulfated arabinopyranosyl moiety in the oligosaccharide chain at C-1 of the steroid skeleton underlined the originality of the compounds of the two\&nbsp;Dracaena\&nbsp;species, and might represent a chemotaxonomic marker of the genus\&nbsp;Dracena. The isolation and structure elucidation of the six new compounds will be presented.},
	author = {Rezgui, A. and Mitaine-Offer, A.-C. and Miyamoto, T. and Tanaka, C. and Paululat, T. and Lacaille-Dubois, M.-A.}
}
