<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">HARROUG, Mohammed-Ridha</style></author><author><style face="normal" font="default" size="100%">Ameddah, Hacene</style></author><author><style face="normal" font="default" size="100%">Mazouz, Hammoudi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Multiscale Computational Design of Ti-6Al-4V/SiC Composite Femoral Stems: SIMP Topology Optimisation, Functionally Graded TPMS Lattices</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Information Systems Engineering and Management</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2026</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://jisem-journal.com/index.php/journal/article/view/15059/7280</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">11</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;
	Aseptic loosening driven by stress shielding remains the principal long-term failure mode of total hip arthroplasty (THA), affecting 10-15% of implants within 15 years and generating annual revision costs exceeding USD 8 billion globally. This study presents an integrated multiscale computational framework for the design of functionally graded femoral stems using Ti-6Al-4V/SiC whisker-reinforced composite materials. The framework systematically couples seven sequential modules : (M1) Halpin-Tsai micromechanical characterisation of three material systems Ti-6Al-4V, Ti/SiC 20 vol%, and Ti/SiC 40 vol%; (M2) analytical beam stress analysis under ISO 7206-4 oblique cantilever loading; (M3) SIMP topology optimisation at V* = 0.70 achieving 30% mass reduction (C/C₀= 0.37), (M4) TPMS lattice homogenisation for four architectures (Gyroid, Diamond, Cubic, Octet) with a corrected stress shielding index (SSI_Gyroid = +11.1%) representing an 87% reduction from monolithic Ti-6Al-4V (SSI = 82.5%), (M5) multiaxial fatigue analysis combining Rainflow cycle counting, modified Goodman criterion, and dual Miner damage reporting (D_ISO = 0.001-0.018; D_full = 0.117-1.426. The Ti/SiC 20 vol% composite in a functionally graded Gyroid architecture emerges as the optimal clinical configuration, uniquely satisfying all biomechanical, osseointegration, and SLM fabricability requirements simultaneously.Keywords:total hip arthroplasty; stress shielding; SIMP topology optimisation; TPMS lattice; Ti-6Al-4V/SiC composite; Goodman criterion; Miner damage; functionally graded implant.
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