This paper aims to evaluate the effect of poultry droppings waste on the different life stage of Eisenia fetida earthworm to protect them from hazardous doses. Adults, juveniles and cocoons were exposed during 90 days to increased doses of poultry droppings (0, 10, 20, 50 and 100 g), added to 250 g of culture substrate. The biological parameters, like mortality, body length, fresh biomass, and cocoons hatching were affected by the organic waste doses and the exposure time. Both poultry droppings doses 10 g (4%) and 20 g (8%) were the less toxic to the cocoons hatching and to the adults' and juveniles' growth. While the two doses, 50 g (20%) and 100 g (40%), had a negative impact on the cocoon hatchability and a toxic effect on the juveniles and adults. Otherwise, the poultry droppings dose 100 g was lethal for the all life stage of E. fetida.