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Publications by Author: Blanc, Aurélien

2014
RofiaMezaache, Harkat H, Obszynski J, Benkouider A, Blanc A, Weibel J-M, Pale P. Copper(II) bromide as an efficient catalyst for acetal to bisarylmethyl ether interconversion. Tetrahedron LettersTetrahedron Letters. 2014;55 :7167-7171.Abstract
Transprotection of acetals to bis(methoxyphenyl)methyl (BMPM) ethers can be efficiently achieved in the presence of copper dibromide as catalyst in acetonitrile at room temperature. Acetals are conveniently and selectively converted to the corresponding mono-protected diol with bis(methoxyphenyl)methyl isopropyl ether (BMPMOiPr) as the reagent. This new practical reagent allows the BMPM transfer to 1,3-dioxolanes or 1,3-dioxanes under copper catalysis. The reaction conditions are also very mild and tolerant to various functional groups, including other protecting groups.
2011
Specklin S, Gallier F, Mezaache R, Harkat H, Yénimégué A, Weibel J-M, Blanc A, Pale P. Copper(II) Bromide as Efficient Catalyst for Silyl- to Bisarylmethyl Ethers Interconversion (Transprotection). Tetrahedron LettersTetrahedron Letters. 2011;52 :5820-5823.Abstract
Primary and secondary silylated alcohols are easily converted to bis(methoxyphenyl)methyl (BMPM) ethers in good yields using CuBr2 as catalyst in acetonitrile at room temperature. Various other protecting groups are compatible with this mild and convenient process. Graphical abstract Primary and secondary silylated alcohols are easily and rapidly converted to bis(methoxyphenyl)methyl (BMPM) ethers in good yields using CuBr2 as catalyst in acetonitrile at room temperature. Various other protecting groups are compatible with this mild and convenient process.