Citation:
Specklin S, Gallier F, Mezaache R, Harkat H, Yénimégué A, Weibel J-M, Blanc A, Pale P. Copper(II) Bromide as Efficient Catalyst for Silyl- to Bisarylmethyl Ethers Interconversion (Transprotection). Tetrahedron LettersTetrahedron Letters. 2011;52 :5820-5823.
Date Published:
09 2011Abstract:
Primary and secondary silylated alcohols are easily converted to bis(methoxyphenyl)methyl (BMPM) ethers in good yields using CuBr2 as catalyst in acetonitrile at room temperature. Various other protecting groups are compatible with this mild and convenient process. Graphical abstract Primary and secondary silylated alcohols are easily and rapidly converted to bis(methoxyphenyl)methyl (BMPM) ethers in good yields using CuBr2 as catalyst in acetonitrile at room temperature. Various other protecting groups are compatible with this mild and convenient process.