Publications

2021
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563-22576.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563–22576.Abstract
Hexavalent chromium (CrVI) is an environmental pollutant and an endocrine-disrupting metal. Se and Zn are essential trace elements, known to play a crucial role in thyroid homeostasis. However, there is a lack of data reporting thyrotoxicity during gestation. In this study, we investigated the protective effects of selenium and zinc against potassium dichromate–induced thyrotoxicity in pregnant Wistar rats. Thirty pregnant Wistar rats were divided into control and four treated groups receiving subcutaneously (s.c) on the 3rd day of pregnancy, K2Cr2O7 (10 mg/kg, s.c) alone, or in association with Se (0.3 mg/kg, s.c), ZnCl2 (20 mg/kg, s.c), or both of them simultaneously. The hormonal profile, oxidative stress biomarkers, DNA damage, and histological modifications were evaluated. Our main findings showed that K2Cr2O7 promoted hypothyroidism, oxidative stress, genotoxicity, and histological alterations in the thyroid gland. The co-treatment with Se or ZnCl2 has mitigated K2Cr2O7-induced thyrotoxicity in pregnant Wistar rats by exhibiting antioxidant and genoprotective effects. However, the combined co-treatment of both of them was less thyroprotective, and therefore, further investigations on the synergetic interaction of Se and Zn against CrVI toxicity using different doses and exposure routes are required.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563-22576.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563–22576.Abstract
Hexavalent chromium (CrVI) is an environmental pollutant and an endocrine-disrupting metal. Se and Zn are essential trace elements, known to play a crucial role in thyroid homeostasis. However, there is a lack of data reporting thyrotoxicity during gestation. In this study, we investigated the protective effects of selenium and zinc against potassium dichromate–induced thyrotoxicity in pregnant Wistar rats. Thirty pregnant Wistar rats were divided into control and four treated groups receiving subcutaneously (s.c) on the 3rd day of pregnancy, K2Cr2O7 (10 mg/kg, s.c) alone, or in association with Se (0.3 mg/kg, s.c), ZnCl2 (20 mg/kg, s.c), or both of them simultaneously. The hormonal profile, oxidative stress biomarkers, DNA damage, and histological modifications were evaluated. Our main findings showed that K2Cr2O7 promoted hypothyroidism, oxidative stress, genotoxicity, and histological alterations in the thyroid gland. The co-treatment with Se or ZnCl2 has mitigated K2Cr2O7-induced thyrotoxicity in pregnant Wistar rats by exhibiting antioxidant and genoprotective effects. However, the combined co-treatment of both of them was less thyroprotective, and therefore, further investigations on the synergetic interaction of Se and Zn against CrVI toxicity using different doses and exposure routes are required.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563-22576.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563–22576.Abstract
Hexavalent chromium (CrVI) is an environmental pollutant and an endocrine-disrupting metal. Se and Zn are essential trace elements, known to play a crucial role in thyroid homeostasis. However, there is a lack of data reporting thyrotoxicity during gestation. In this study, we investigated the protective effects of selenium and zinc against potassium dichromate–induced thyrotoxicity in pregnant Wistar rats. Thirty pregnant Wistar rats were divided into control and four treated groups receiving subcutaneously (s.c) on the 3rd day of pregnancy, K2Cr2O7 (10 mg/kg, s.c) alone, or in association with Se (0.3 mg/kg, s.c), ZnCl2 (20 mg/kg, s.c), or both of them simultaneously. The hormonal profile, oxidative stress biomarkers, DNA damage, and histological modifications were evaluated. Our main findings showed that K2Cr2O7 promoted hypothyroidism, oxidative stress, genotoxicity, and histological alterations in the thyroid gland. The co-treatment with Se or ZnCl2 has mitigated K2Cr2O7-induced thyrotoxicity in pregnant Wistar rats by exhibiting antioxidant and genoprotective effects. However, the combined co-treatment of both of them was less thyroprotective, and therefore, further investigations on the synergetic interaction of Se and Zn against CrVI toxicity using different doses and exposure routes are required.
Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environmental Science and Pollution ResearchEnvironmental Science and Pollution Research. 2021;28 :22563-22576.
Khedidja A, Boudoukha A. Quality assessment of shallow groundwater for irrigation purposes in Tadjenanet–Chelghoum Laid area (Eastern Algeria). International Journal of River Basin ManagementInternational Journal of River Basin Management. 2021;19 :141-148.
Khedidja A, Boudoukha A. Quality assessment of shallow groundwater for irrigation purposes in Tadjenanet–Chelghoum Laid area (Eastern Algeria). International Journal of River Basin ManagementInternational Journal of River Basin Management. 2021;19 :141-148.
Ikhlef M, Bendjerad A, Boukhtache S, Abdelhadi B, Lahmar A. Refined Approach in Jiles-Atherton Model for Ferromagnetic Sheet Under the Tensile Stress. Journal of Superconductivity and Novel MagnetismJournal of Superconductivity and Novel Magnetism. 2021;34 :227-234.
Ikhlef M, Bendjerad A, Boukhtache S, Abdelhadi B, Lahmar A. Refined Approach in Jiles-Atherton Model for Ferromagnetic Sheet Under the Tensile Stress. Journal of Superconductivity and Novel MagnetismJournal of Superconductivity and Novel Magnetism. 2021;34 :227-234.
Ikhlef M, Bendjerad A, Boukhtache S, Abdelhadi B, Lahmar A. Refined Approach in Jiles-Atherton Model for Ferromagnetic Sheet Under the Tensile Stress. Journal of Superconductivity and Novel MagnetismJournal of Superconductivity and Novel Magnetism. 2021;34 :227-234.
Ikhlef M, Bendjerad A, Boukhtache S, Abdelhadi B, Lahmar A. Refined Approach in Jiles-Atherton Model for Ferromagnetic Sheet Under the Tensile Stress. Journal of Superconductivity and Novel MagnetismJournal of Superconductivity and Novel Magnetism. 2021;34 :227-234.
Ikhlef M, Bendjerad A, Boukhtache S, Abdelhadi B, Lahmar A. Refined Approach in Jiles-Atherton Model for Ferromagnetic Sheet Under the Tensile Stress. Journal of Superconductivity and Novel MagnetismJournal of Superconductivity and Novel Magnetism. 2021;34 :227-234.
Hefaidh H, Mébarek D, Negrou B, Driss Z. Reliability degradation prediction of photovoltaic modules based on dependability methods. International Journal of Quality & Reliability ManagementInternational Journal of Quality & Reliability Management. 2021.
Hefaidh H, Mébarek D, Negrou B, Driss Z. Reliability degradation prediction of photovoltaic modules based on dependability methods. International Journal of Quality & Reliability ManagementInternational Journal of Quality & Reliability Management. 2021.
Hefaidh H, Mébarek D, Negrou B, Driss Z. Reliability degradation prediction of photovoltaic modules based on dependability methods. International Journal of Quality & Reliability ManagementInternational Journal of Quality & Reliability Management. 2021.
Hefaidh H, Mébarek D, Negrou B, Driss Z. Reliability degradation prediction of photovoltaic modules based on dependability methods. International Journal of Quality & Reliability ManagementInternational Journal of Quality & Reliability Management. 2021.
Aouadj W, Abdessemed M-R, Seghir R. A Reliable Behavioral Model: Optimizing Energy Consumption and Object Clustering Quality by Naïve Robots. International Journal of Swarm Intelligence Research (IJSIR)International Journal of Swarm Intelligence Research (IJSIR). 2021;12 :125-145.
Aouadj W, Abdessemed M-R, Seghir R. A Reliable Behavioral Model: Optimizing Energy Consumption and Object Clustering Quality by Naïve Robots. International Journal of Swarm Intelligence Research (IJSIR)International Journal of Swarm Intelligence Research (IJSIR). 2021;12 :125-145.

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