Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

Wavelets are known particularly to be an effective tool for extracting discriminative features in the scattered RF signals of both solid and gaseous emboli. However, the selection of an appropriate mother wavelet for the signal being analyzed is an important criterion. This offers the possibility to perform an optimization procedure to obtain the best wavelet. The purpose of the study is to propose a new approach to classify microembolic echoes using a discrete wavelet transform (DWT) based on genetic algorithm optimization and support vector machine (SVM) classifier. The experimental setup consists of a flow phantom (ATSLaB) containing a tube of 6 mm in diameter. In order to mimic the ultrasonic behavior of gaseous emboli, contrast agents consisting of microbubbles are used in our experimental setup. However, to mimic the behavior of the solid emboli we have used the Doppler fluid which contains particles with scatter characteristics comparable to red blood cells. The acquisitions are carried out at 2 MHz and 3.5 MHz transmit frequency. Ultrasound waves are transmitted at different intensities corresponding to mechanical indices (MI) of 0.21 and 0.42 for the transmit frequency of 2 MHz, and 0.31 and 0.62 for the transmit frequency of 3.5 MHz. Two concentrations of the contrast agent (100 μl and 200 μl) are diluted into a 100 ml volume of water. The polyphase representation of the discrete wavelet transform (DWT) is exploited in this study. Such representation allows generating a wavelet filter bank from a set of angular parameters, in order to minimize the fitness function based on genetic algorithm optimization and the SVM classifier. The best accuracy classifications of microemboli obtained in this study are equal to 99.90% for 2MHz and to 99.60% for 3.5MHz. These results illustrate that wavelet optimization approach works well for microemboli classification using RF signals.

In this study, pomace olives coming from different mills (Press process, continuous process two-phases and threephases) were used for extraction of oils. The highest oil yield (12.92%) was obtained with pomace olives coming from press process. Total contents of phenolics (13.47 - 21.25 mg GAE/100 g oil) and flavonoids (5.90 - 12.52mg QE/100 g oil)were determined spectrophotometrically. The pomace olive oil “POO3” (Pomace olive coming from 3-phases system) presented the highest phenolic, flavonoid contents and showed the highest DPPH, ABTS scavenging, metal chelating activity. In vitro anticholinesterase activity, the olive pomace oils showed moderate inhibition against AChE and BChE which are the key enzymes taking place in pathogenesis of Alzheimer’s disease. These results showed that the tested oils can be considered as sources of natural antioxidant, as well as moderate anticholinesterase agents.

In this study, pomace olives coming from different mills (Press process, continuous process two-phases and threephases) were used for extraction of oils. The highest oil yield (12.92%) was obtained with pomace olives coming from press process. Total contents of phenolics (13.47 - 21.25 mg GAE/100 g oil) and flavonoids (5.90 - 12.52mg QE/100 g oil)were determined spectrophotometrically. The pomace olive oil “POO3” (Pomace olive coming from 3-phases system) presented the highest phenolic, flavonoid contents and showed the highest DPPH, ABTS scavenging, metal chelating activity. In vitro anticholinesterase activity, the olive pomace oils showed moderate inhibition against AChE and BChE which are the key enzymes taking place in pathogenesis of Alzheimer’s disease. These results showed that the tested oils can be considered as sources of natural antioxidant, as well as moderate anticholinesterase agents.

In this study, pomace olives coming from different mills (Press process, continuous process two-phases and threephases) were used for extraction of oils. The highest oil yield (12.92%) was obtained with pomace olives coming from press process. Total contents of phenolics (13.47 - 21.25 mg GAE/100 g oil) and flavonoids (5.90 - 12.52mg QE/100 g oil)were determined spectrophotometrically. The pomace olive oil “POO3” (Pomace olive coming from 3-phases system) presented the highest phenolic, flavonoid contents and showed the highest DPPH, ABTS scavenging, metal chelating activity. In vitro anticholinesterase activity, the olive pomace oils showed moderate inhibition against AChE and BChE which are the key enzymes taking place in pathogenesis of Alzheimer’s disease. These results showed that the tested oils can be considered as sources of natural antioxidant, as well as moderate anticholinesterase agents.