Contrairement à l’abstention-surveillance, la surveillance active est une modalité de prise en charge curative. Elle vise à retarder le traitement d’une tumeur peu agressive jusqu’au moment où elle le deviendra tout en restant dans la fenêtre de curabilité de la maladie. À travers une lecture de littératures, nous allons essayer de maitre la lumière sur la place et les modalités de la surveillance active, dans les groupes favorables des cancers de la prostate et de répondre aux questions suivantes : Pourquoi la surveillance active ? Pour qui ? Comment l’instauré ? et quand doit-on l’arrêter ? La majorité des essais, cliniques publiés s’accordent à dire, que la surveillance active est une attitude parfaitement adaptée aux patients du groupe favorable d’AMICO, voire même une partie du groupe intermédiaire bas risque. Les résultats en matière de survie globale et d’évènement métastatiques, sont similaires à ceux des patients traités d’emblée par chirurgie et ou radiothérapie, avec en plus moins de toxicité. La surveillance est basée essentiellement sur le dosage périodique du PSA, rebiopsie selon des protocoles propres à chaque équipe. La décision du passage aux traitements invasifs, sera conditionnée par la progression du score Gleason, selon des algorithmes dont certains, sont déjà validés à l’international. La surveillance active, doit faire partie intégrante des décisions de prise en charge des adénocarcinomes prostatiques localisés favorables. Cette attitude nous permet, d’éviter de surtraiter un grand nombre, de petites lésions non évolutives, tout en ayant la possibilité et les moyens, de rattraper les lésions qui progressent.

Contrairement à l’abstention-surveillance, la surveillance active est une modalité de prise en charge curative. Elle vise à retarder le traitement d’une tumeur peu agressive jusqu’au moment où elle le deviendra tout en restant dans la fenêtre de curabilité de la maladie. À travers une lecture de littératures, nous allons essayer de maitre la lumière sur la place et les modalités de la surveillance active, dans les groupes favorables des cancers de la prostate et de répondre aux questions suivantes : Pourquoi la surveillance active ? Pour qui ? Comment l’instauré ? et quand doit-on l’arrêter ? La majorité des essais, cliniques publiés s’accordent à dire, que la surveillance active est une attitude parfaitement adaptée aux patients du groupe favorable d’AMICO, voire même une partie du groupe intermédiaire bas risque. Les résultats en matière de survie globale et d’évènement métastatiques, sont similaires à ceux des patients traités d’emblée par chirurgie et ou radiothérapie, avec en plus moins de toxicité. La surveillance est basée essentiellement sur le dosage périodique du PSA, rebiopsie selon des protocoles propres à chaque équipe. La décision du passage aux traitements invasifs, sera conditionnée par la progression du score Gleason, selon des algorithmes dont certains, sont déjà validés à l’international. La surveillance active, doit faire partie intégrante des décisions de prise en charge des adénocarcinomes prostatiques localisés favorables. Cette attitude nous permet, d’éviter de surtraiter un grand nombre, de petites lésions non évolutives, tout en ayant la possibilité et les moyens, de rattraper les lésions qui progressent.

Image classification has been one of the most widely topic in artificial intelligence, deep models need larger datasets and powerful hardware to improve the highperformance classification. ImageNet Challenge was started in 2010 to classify 100,000 test images into 1000 different classes. Tiny ImageNet challenge is similar to ImageNet challenge, where images are taken from the standard ImageNet and resized to be 64x64. In this paper a fine-tuned Xception to classify images into the 200 classes is presented using the standard Tiny ImageNet dataset, the down-sampling (64x64) of images and the low similarity inter-class makes feature extraction and classification difficult and more challenging. We used a transfer learning algorithm to fine-tune the Xception architecture using the Extreme version of the Inception module to achieve a high validation accuracy of 65.14%.

Image classification has been one of the most widely topic in artificial intelligence, deep models need larger datasets and powerful hardware to improve the highperformance classification. ImageNet Challenge was started in 2010 to classify 100,000 test images into 1000 different classes. Tiny ImageNet challenge is similar to ImageNet challenge, where images are taken from the standard ImageNet and resized to be 64x64. In this paper a fine-tuned Xception to classify images into the 200 classes is presented using the standard Tiny ImageNet dataset, the down-sampling (64x64) of images and the low similarity inter-class makes feature extraction and classification difficult and more challenging. We used a transfer learning algorithm to fine-tune the Xception architecture using the Extreme version of the Inception module to achieve a high validation accuracy of 65.14%.

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order to find effective solutions. One of the promising therapeutic approaches is the search for bioactive molecules with few side effects that display antiviral properties in natural sources like medicinal plants and vegetables. Several computational and experimental studies indicated that flavonoids especially flavonols and their derivatives constitute effective viral enzyme inhibitors and possess interesting antiviral activities. In this context, the present study reviews the efficacy of many dietary flavonols as potential antiviral drugs targeting the SARS-CoV-2 enzymes and proteins including Chymotrypsin-Like Protease (3CL^pro), Papain Like protease (PL^pro), Spike protein (S protein) and RNA-dependent RNA polymerase (RdRp), and also their ability to interact with the angiotensin-converting enzyme II (ACE2) receptor. The relationship between flavonol structures and their SARS-CoV-2 antiviral effects were discussed. On the other hand, the immunomodulatory, the anti-inflammatory and the antiviral effects of secondary metabolites from this class of flavonoids were reported. Also, their bioavailability limitations and toxicity were predicted.

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order to find effective solutions. One of the promising therapeutic approaches is the search for bioactive molecules with few side effects that display antiviral properties in natural sources like medicinal plants and vegetables. Several computational and experimental studies indicated that flavonoids especially flavonols and their derivatives constitute effective viral enzyme inhibitors and possess interesting antiviral activities. In this context, the present study reviews the efficacy of many dietary flavonols as potential antiviral drugs targeting the SARS-CoV-2 enzymes and proteins including Chymotrypsin-Like Protease (3CL^pro), Papain Like protease (PL^pro), Spike protein (S protein) and RNA-dependent RNA polymerase (RdRp), and also their ability to interact with the angiotensin-converting enzyme II (ACE2) receptor. The relationship between flavonol structures and their SARS-CoV-2 antiviral effects were discussed. On the other hand, the immunomodulatory, the anti-inflammatory and the antiviral effects of secondary metabolites from this class of flavonoids were reported. Also, their bioavailability limitations and toxicity were predicted.

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order to find effective solutions. One of the promising therapeutic approaches is the search for bioactive molecules with few side effects that display antiviral properties in natural sources like medicinal plants and vegetables. Several computational and experimental studies indicated that flavonoids especially flavonols and their derivatives constitute effective viral enzyme inhibitors and possess interesting antiviral activities. In this context, the present study reviews the efficacy of many dietary flavonols as potential antiviral drugs targeting the SARS-CoV-2 enzymes and proteins including Chymotrypsin-Like Protease (3CL^pro), Papain Like protease (PL^pro), Spike protein (S protein) and RNA-dependent RNA polymerase (RdRp), and also their ability to interact with the angiotensin-converting enzyme II (ACE2) receptor. The relationship between flavonol structures and their SARS-CoV-2 antiviral effects were discussed. On the other hand, the immunomodulatory, the anti-inflammatory and the antiviral effects of secondary metabolites from this class of flavonoids were reported. Also, their bioavailability limitations and toxicity were predicted.

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order to find effective solutions. One of the promising therapeutic approaches is the search for bioactive molecules with few side effects that display antiviral properties in natural sources like medicinal plants and vegetables. Several computational and experimental studies indicated that flavonoids especially flavonols and their derivatives constitute effective viral enzyme inhibitors and possess interesting antiviral activities. In this context, the present study reviews the efficacy of many dietary flavonols as potential antiviral drugs targeting the SARS-CoV-2 enzymes and proteins including Chymotrypsin-Like Protease (3CL^pro), Papain Like protease (PL^pro), Spike protein (S protein) and RNA-dependent RNA polymerase (RdRp), and also their ability to interact with the angiotensin-converting enzyme II (ACE2) receptor. The relationship between flavonol structures and their SARS-CoV-2 antiviral effects were discussed. On the other hand, the immunomodulatory, the anti-inflammatory and the antiviral effects of secondary metabolites from this class of flavonoids were reported. Also, their bioavailability limitations and toxicity were predicted.

The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The lack of efficacious drugs and vaccines against this viral infection created a challenge for scientific researchers in order to find effective solutions. One of the promising therapeutic approaches is the search for bioactive molecules with few side effects that display antiviral properties in natural sources like medicinal plants and vegetables. Several computational and experimental studies indicated that flavonoids especially flavonols and their derivatives constitute effective viral enzyme inhibitors and possess interesting antiviral activities. In this context, the present study reviews the efficacy of many dietary flavonols as potential antiviral drugs targeting the SARS-CoV-2 enzymes and proteins including Chymotrypsin-Like Protease (3CL^pro), Papain Like protease (PL^pro), Spike protein (S protein) and RNA-dependent RNA polymerase (RdRp), and also their ability to interact with the angiotensin-converting enzyme II (ACE2) receptor. The relationship between flavonol structures and their SARS-CoV-2 antiviral effects were discussed. On the other hand, the immunomodulatory, the anti-inflammatory and the antiviral effects of secondary metabolites from this class of flavonoids were reported. Also, their bioavailability limitations and toxicity were predicted.

Floods become major concerns in most gobe regions due to socio-economic and environmental consequences caused by these phenomena in recent decades. Most Algerian cities are exposed to flood risks and suffered from its consequences. The purpose of this paper is the spatialization of flood hazard in the city of Chemora (Algeria) by hydraulic modelling in a GIS environment whose objective is prevention, which requires a set of hydrological and hydraulic informations in order to achieve a comprehensive and effective management.

Floods become major concerns in most gobe regions due to socio-economic and environmental consequences caused by these phenomena in recent decades. Most Algerian cities are exposed to flood risks and suffered from its consequences. The purpose of this paper is the spatialization of flood hazard in the city of Chemora (Algeria) by hydraulic modelling in a GIS environment whose objective is prevention, which requires a set of hydrological and hydraulic informations in order to achieve a comprehensive and effective management.

Floods become major concerns in most gobe regions due to socio-economic and environmental consequences caused by these phenomena in recent decades. Most Algerian cities are exposed to flood risks and suffered from its consequences. The purpose of this paper is the spatialization of flood hazard in the city of Chemora (Algeria) by hydraulic modelling in a GIS environment whose objective is prevention, which requires a set of hydrological and hydraulic informations in order to achieve a comprehensive and effective management.

Floods become major concerns in most gobe regions due to socio-economic and environmental consequences caused by these phenomena in recent decades. Most Algerian cities are exposed to flood risks and suffered from its consequences. The purpose of this paper is the spatialization of flood hazard in the city of Chemora (Algeria) by hydraulic modelling in a GIS environment whose objective is prevention, which requires a set of hydrological and hydraulic informations in order to achieve a comprehensive and effective management.

As renewable energy elucidation, the solar refrigeration of fruits such as date palm is a storage alternate to preserve food in healthy parameters of conditioning. This statistical and numeric study investigates the energy gain cost case around the diverse dimensions’ models of positive cold stores (02, 04, and 06 cold rooms), concerning energetic disparity and numerous financial fluctuations of the applied systems. The results of computation and analysis regarding panels of construction, equipment, consumption, and maintenance for classic, absorption, and adsorption refrigeration systems that conserve dates palm into these three cold stores. In the end, the comparison of technical and economic elements in tables and figures by enumerating their advantages and inconveniences. Classic Bitzer, Absorption WFC SC 5, and Adsorption AG ACS 15 and 08 are models in which their evaluation is relating to their costs. In Biskra, these results mean that adsorption chiller termed AG ACS (15 plus 08) is illustrious by its parameters of simplicity, lifespan, safety, and security, valued to 1147.5 €/m² and median cost up ten years of using is 92972 €

As renewable energy elucidation, the solar refrigeration of fruits such as date palm is a storage alternate to preserve food in healthy parameters of conditioning. This statistical and numeric study investigates the energy gain cost case around the diverse dimensions’ models of positive cold stores (02, 04, and 06 cold rooms), concerning energetic disparity and numerous financial fluctuations of the applied systems. The results of computation and analysis regarding panels of construction, equipment, consumption, and maintenance for classic, absorption, and adsorption refrigeration systems that conserve dates palm into these three cold stores. In the end, the comparison of technical and economic elements in tables and figures by enumerating their advantages and inconveniences. Classic Bitzer, Absorption WFC SC 5, and Adsorption AG ACS 15 and 08 are models in which their evaluation is relating to their costs. In Biskra, these results mean that adsorption chiller termed AG ACS (15 plus 08) is illustrious by its parameters of simplicity, lifespan, safety, and security, valued to 1147.5 €/m² and median cost up ten years of using is 92972 €

Today’s, and near future, communication networks rely heavily on capacity expansion to keep pace with the massive number of mobile devices and ever-increasing mobile traffic. This expansion can be achieved through three major ingredients, namely, adding more wireless-spectrum, efficient usage of this spectrum, and adequate networks’ architectures. In this paper, a proposition for integrating these three ingredients in a cognitive-radio-inspired framework is presented. The focus is on the integration of the idle spectrum resources of different wireless networks into a single mobile heterogeneous wireless network. This framework is based on a conceptual network-architecture articulated with a generic and cooperative spectrum-harvesting scheme. The former brings the necessary agility for such heterogeneous environments, the latter keeps the network supplied with the vital spectrum resources. In our proposal, we make use of cross-correlated sequences (CCSs) for context-aware events’ signaling purposes. This choice is motivated by the particularly interesting characteristics of CCSs, namely, duration shortness, robustness to bad radio conditions, detection rather than decoding, and low probability of collision. As an illustration, we propose a reporting and detection scheme, in the context of OFDMA systems, and provide performance results from simulations to validate our proposal.

Today’s, and near future, communication networks rely heavily on capacity expansion to keep pace with the massive number of mobile devices and ever-increasing mobile traffic. This expansion can be achieved through three major ingredients, namely, adding more wireless-spectrum, efficient usage of this spectrum, and adequate networks’ architectures. In this paper, a proposition for integrating these three ingredients in a cognitive-radio-inspired framework is presented. The focus is on the integration of the idle spectrum resources of different wireless networks into a single mobile heterogeneous wireless network. This framework is based on a conceptual network-architecture articulated with a generic and cooperative spectrum-harvesting scheme. The former brings the necessary agility for such heterogeneous environments, the latter keeps the network supplied with the vital spectrum resources. In our proposal, we make use of cross-correlated sequences (CCSs) for context-aware events’ signaling purposes. This choice is motivated by the particularly interesting characteristics of CCSs, namely, duration shortness, robustness to bad radio conditions, detection rather than decoding, and low probability of collision. As an illustration, we propose a reporting and detection scheme, in the context of OFDMA systems, and provide performance results from simulations to validate our proposal.

Today’s, and near future, communication networks rely heavily on capacity expansion to keep pace with the massive number of mobile devices and ever-increasing mobile traffic. This expansion can be achieved through three major ingredients, namely, adding more wireless-spectrum, efficient usage of this spectrum, and adequate networks’ architectures. In this paper, a proposition for integrating these three ingredients in a cognitive-radio-inspired framework is presented. The focus is on the integration of the idle spectrum resources of different wireless networks into a single mobile heterogeneous wireless network. This framework is based on a conceptual network-architecture articulated with a generic and cooperative spectrum-harvesting scheme. The former brings the necessary agility for such heterogeneous environments, the latter keeps the network supplied with the vital spectrum resources. In our proposal, we make use of cross-correlated sequences (CCSs) for context-aware events’ signaling purposes. This choice is motivated by the particularly interesting characteristics of CCSs, namely, duration shortness, robustness to bad radio conditions, detection rather than decoding, and low probability of collision. As an illustration, we propose a reporting and detection scheme, in the context of OFDMA systems, and provide performance results from simulations to validate our proposal.

The direct power control of the doubly fed induction generator using conventional controllers is characterized by unsatisfactory performance: high ripples of stator powers and sensitivity to parametric variations. Among the most evoked control strategies adopted in this field to overcome these drawbacks presented in classical drive, it is worth mentioning the use of the higher law sliding mode developed on the super twisting algorithm associated with the fuzzy logic control in order to realize optimal command performance, Finally, the efficiency of the envisaged control scheme, is investigated against. The proposed regulation scheme is efficient in reducing the powers ripples; successfully suppress chatter and the effects of parametric variations that do not affect the performance of the regulation.

The direct power control of the doubly fed induction generator using conventional controllers is characterized by unsatisfactory performance: high ripples of stator powers and sensitivity to parametric variations. Among the most evoked control strategies adopted in this field to overcome these drawbacks presented in classical drive, it is worth mentioning the use of the higher law sliding mode developed on the super twisting algorithm associated with the fuzzy logic control in order to realize optimal command performance, Finally, the efficiency of the envisaged control scheme, is investigated against. The proposed regulation scheme is efficient in reducing the powers ripples; successfully suppress chatter and the effects of parametric variations that do not affect the performance of the regulation.